Testing Pre-Annotation to Help Non-Experts Identify Drug-Drug Interactions Mentioned in Drug Product Labeling
نویسندگان
چکیده
Drug-drug interactions (DDIs) are defined as clinically meaningful alterations in the exposure and response to a drug (called object drug) that has occurred as a result of the co-administration of another drug (called precipitant drug). According a 2011 study, drug-drug interactions (DDIs) are responsible for roughly 220,000 hospital admissions per year (Percha and Altman 2013). However, this number is possible to be an underestimate due to the uncertainty of the impact of DDI on adverse patient outcomes (Becker et al. 2007).
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